Article
Ribosomal Protein S12e Has a Distinct Function in Cell Competition.
Developmental cell - 8 Jan 2018
Kale Abhijit, Ji Zhejun, Kiparaki Marianthi, Blanco Jorge, Rimesso Gerard, Flibotte Stephane, Baker Nicholas E
Abstract excerpt
Wild-type Drosophila cells can remove cells heterozygous for ribosomal protein mutations (known as "Minute" mutant cells) from genetic mosaics, a process termed cell competition. The ribosomal protein S12 was unusual because cells heterozygous for rpS12 mutations were not competed by wild-type, and a viable missense mutation in rpS12 protected Minute cells from cell competition with wild-type cells. Furthermore,...
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