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Article

Snapshots of a molecular swivel in action.

Nucleic acids research - 1 Jun 2018

Trejo Caitlin S, Rock Ronald S, Stark W Marshall, Boocock Martin R, Rice Phoebe A

Abstract excerpt

Members of the serine family of site-specific recombinases exchange DNA strands via 180° rotation about a central protein-protein interface. Modeling of this process has been hampered by the lack of structures in more than one rotational state for any individual serine recombinase. Here we report crystal structures of the catalytic domains of four constitutively active mutants of the serine recombinase Sin,...

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Identifiers

PMID: 29315406
DOI: 10.1093/nar/gkx1309
PMCID: PMC6007550

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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