Article
In Thai Nationals, the ApoE4 Allele Affects Multiple Domains of Neuropsychological, Biobehavioral, and Social Functioning Thereby Contributing to Alzheimer's Disorder, while the ApoE3 Allele Protects Against Neuropsychiatric Symptoms and Psychosocial Deficits.
Molecular neurobiology - 1 Aug 2018
Tangwongchai Sookjaroen, Supasitthumrong Thitiporn, Hemrunroj Solaphat, Tunvirachaisakul Chavit, Chuchuen Phenphichcha, Houngngam Natnicha, Snabboon Thiti, Tawankanjanachot Ittipol, Likitchareon Yuthachai, Phanthumchindad Kamman, Maes Michael
Abstract excerpt
The apolipoprotein E epsilon 4 (ApoE4) allele is the strongest genetic risk factor for Alzheimer's disorder (AD) and is associated with semantic and episodic memory deficits. The aim of this study was to examine the associations between ApoE alleles (E2, E3, E4) and genotypes and neuropsychological tests, behavioral functions, and dementia symptoms as assessed using Consortium to Establish a Registry for...
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