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Article

Variant evolution graph: Can we infer how SARS-CoV-2 variants are evolving?

PloS one - 1 Jan 2025

Das Badhan, Heath Lenwood S

Abstract excerpt

The SARS-CoV-2 virus has undergone extensive mutations over time, resulting in considerable genetic diversity among circulating strains. This diversity directly affects important viral characteristics, such as transmissibility and disease severity. During a viral outbreak, the rapid mutation rate produces a large cloud of variants, referred to as a viral quasispecies. However, many variants are lost due to the...

Read the complete abstract on PubMed

Topics

SARS-CoV-2
Humans
Phylogeny
COVID-19
Evolution, Molecular
Genome, Viral
Mutation
Genetic Variation

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Identifiers

PMID: 40489481
DOI: 10.1371/journal.pone.0323970
PMCID: PMC12148141

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