Conserved Citrullinating Exoenzymes in Porphyromonas Species

Abstract excerpt

Porphyromonas gingivalis is one of the major oral pathogens implicated in the widespread inflammatory disorder periodontitis. Moreover, in recent years, P. gingivalis has been associated with the autoimmune disease rheumatoid arthritis. The peptidylarginine deiminase enzyme of P. gingivalis (PPAD) is a major virulence factor that catalyzes the citrullination of both bacterial and host proteins, potentially...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Oral Health Pathology and Treatment
• Share to Oral microbiology and periodontitis research
• Share to Streptococcal Infections and Treatments