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Article

A Holistic Approach to AKI: Integrating Clinical and Molecular Data in the Human Kidney.

Seminars in nephrology - 1 Nov 2025

Schaub Jennifer A, Alaba Mathew, Kretzler Matthias

Abstract excerpt

Despite intensive research efforts, acute kidney injury (AKI) is a common clinical syndrome that has limited treatment options apart from supportive care. The increasing availability of molecular interrogation data from patients with Acute Kidney Injury provides an unparalleled opportunity to leverage systems biology approaches. In this review, we discuss the challenges with AKI research, explain how systems...

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Identifiers

PMID: 40925758
DOI: 10.1016/j.semnephrol.2025.151663
PMCID: PMC12435924

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