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Systematic review of pharmacogenomics and adverse drug reactions in paediatric oncology patients.

Pediatric blood & cancer - 1 Apr 2018

Conyers Rachel, Devaraja Subalatha, Elliott David

Abstract excerpt

Many paediatric patients with cancer experience significant chemotherapy side effects. Predisposition to drug reactions is governed by single nucleotide polymorphisms (SNPs). We performed a systematic review of the literature from 2006 through 2016. Outcomes of interest included patient characteristics, cancer type drug of interest, genes investigated, toxicity identified and genetic polymorphisms implicated. The...

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Child
Child, Preschool
Adolescent
Antineoplastic Agents
Infant
Infant, Newborn

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Pharmacogenomic Testing

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PMID: 29286579
DOI: 10.1002/pbc.26937

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