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Article

Molecular Basis for Converting (2S)-Methylsuccinyl-CoA Dehydrogenase into an Oxidase.

Molecules (Basel, Switzerland) - 28 Dec 2017

Burgener Simon, Schwander Thomas, Romero Elvira, Fraaije Marco W, Erb Tobias J

Abstract excerpt

Although flavoenzymes have been studied in detail, the molecular basis of their dioxygen reactivity is only partially understood. The members of the flavin adenosine dinucleotide (FAD)-dependent acyl-CoA dehydrogenase and acyl-CoA oxidase families catalyze similar reactions and share common structural features. However, both enzyme families feature opposing reaction specificities in respect to dioxygen....

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PMID: 29283425
DOI: 10.3390/molecules23010068
PMCID: PMC6017585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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