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Article

Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies

22 Dec 2017

Abstract excerpt

Rottlerin is a natural polyphenolic compound that was initially indicated as a PKCδ inhibitor. However, it was recently revealed that it may target a number of molecules and have biological effects on various cell types and is considered as a possible agent for tumor and cell proliferative diseases. Psoriasis is a chronic inflammatory cutaneous disorder with undefined etiology and is characterized by abnormal...

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PMID: 29272319
DOI: 10.1371/journal.pone.0190051

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