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Article

Differential effects of several phytochemicals and their derivatives on murine keratinocytes in vitro and in vivo: implications for skin cancer prevention.

Carcinogenesis - 1 Jun 2009

Kowalczyk Magdalena C, Walaszek Zbigniew, Kowalczyk Piotr, Kinjo Tatsuya, Hanausek Margaret, Slaga Thomas J

Abstract excerpt

The purpose of our study was to investigate in vitro the potential cancer preventive properties of several phytochemicals, i.e. grape seed extract (GSE), resveratrol (RES), ursolic acid (URA), ellagic acid (ELA), lycopene and N-acetyl-L-cysteine (NAC) to define the mechanisms by which these compounds may inhibit murine skin carcinogenesis. We measured quenching of peroxyl, superoxide and hydroxyl radicals by...

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Identifiers

PMID: 19329757
DOI: 10.1093/carcin/bgp069
PMCID: PMC2691143

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