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Impact of genistein on the gut microbiome of humanized mice and its role in breast tumor inhibition

21 Dec 2017

Abstract excerpt

Since dietary polyphenols can have beneficial effects in prevention and treatment of cancer, we tested the hypothesis that breast cancer patients' intestinal microbiota is modulated by genistein (GE), an isoflavone found in soy, and that microbial alterations may offset the side effects brought about by chemotherapy. We demonstrated successful humanization of germ-free mice by transplanting fecal samples from...

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PMID: 29267377
DOI: 10.1371/journal.pone.0189756

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