Article
Long-term intermittent caloric restriction remodels the gut microbiota in mice genetically prone to breast cancer.
Nutrition (Burbank, Los Angeles County, Calif.) - 1 Oct 2024
Keles Nazim Arda, Dogan Soner, Dogan Aysenur, Sudagidan Mert, Balci Tugce Nur, Cetiner Ozlem, Kavruk Murat, Ozalp Veli Cengiz, Tuna Bilge Guvenc
Abstract excerpt
OBJECTIVES: Gut microbiota dysbiosis is among the risk factors for breast cancer development, together with genetic background and dietary habits. However, caloric restriction has been shown to remodel the gut microbiota and slow tumor growth. Here, we investigated whether the gut microbiota mediates the preventive effects of long-term chronic or intermittent caloric restriction on breast cancer predisposition....
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