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Cryo-Electron Microscopy Structure of Seneca Valley Virus Procapsid

15 Dec 2017

Abstract excerpt

ABSTRACT Seneca Valley virus (SVV), like some other members of the Picornaviridae , forms naturally occurring empty capsids, known as procapsids. Procapsids have the same antigenicity as full virions, so they present an interesting possibility for the formation of stable virus-like particles. Interestingly, although SVV is a livestock pathogen, it has also been found to preferentially infect tumor cells and is...

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PMID: 29263256
DOI: 10.1128/jvi.01927-17

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