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Article

Moloney leukemia virus 10 (MOV10) inhibits the degradation of APOBEC3G through interference with the Vif-mediated ubiquitin-proteasome pathway.

Retrovirology - 19 Dec 2017

Chen Cancan, Ma Xiaocao, Hu Qifei, Li Xinghua, Huang Feng, Zhang Junsong, Pan Ting, Xia Jinyu, Liu Chao, Zhang Hui

Abstract excerpt

BACKGROUND: MOV10 protein has ATP-dependent 5'-3' RNA helicase activity and belongs to the UPF1p superfamily. It can inhibit human immunodeficiency virus type 1 (HIV-1) replication at multiple stages and interact with apolipoprotein-B-mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G or A3G), a member of the cytidine deaminase family that exerts potent inhibitory effects against HIV-1 infection....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to vif Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 29258557
DOI: 10.1186/s12977-017-0382-1
PMCID: PMC5735797

Genes

MOV10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

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Moloney leukemia virus 10 (MOV10) inhibits the degradation of APOBEC3G through interference with the Vif-mediated ubiquitin-proteasome pathway.PMID 29258557Read ↗

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