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Plasmodium yoelii S4/CelTOS is important for sporozoite gliding motility and cell traversal

18 Dec 2017

Abstract excerpt

Gliding motility and cell traversal by the Plasmodium ookinete and sporozoite invasive stages allow penetration of cellular barriers to establish infection of the mosquito vector and mammalian host, respectively. Motility and traversal are not observed in red cell infectious merozoites, and we have previously classified genes that are expressed in sporozoites but not merozoites (S genes) in order to identify...

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PMID: 29253313
DOI: 10.1111/cmi.12817

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