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Article

TRSP is dispensable for the Plasmodium pre-erythrocytic phase

4 Oct 2018

Abstract excerpt

Plasmodium sporozoites deposited in the skin following a mosquito bite must migrate and invade blood vessels to complete their development in the liver. Once in the bloodstream, sporozoites arrest in the liver sinusoids, but the molecular determinants that mediate this specific homing are not yet genetically defined. Here we investigate the involvement of the thrombospondin-related sporozoite protein (TRSP) in...

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PMID: 30305687
DOI: 10.1038/s41598-018-33398-8

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