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Article

Ovarian cancer risk, ALDH2 polymorphism and alcohol drinking: Asian data from the Ovarian Cancer Association Consortium.

Cancer science - 1 Feb 2018

Ugai Tomotaka, Kelemen Linda E, Mizuno Mika, Ong Jue-Sheng, Webb Penelope M, Chenevix-Trench Georgia, Wicklund Kristine G, Doherty Jennifer Anne, Rossing Mary Anne, Thompson Pamela J, Wilkens Lynne R, Carney Michael E, Goodman Marc T, Schildkraut Joellen M, Berchuck Andrew, Cramer Daniel W, Terry Kathryn L, Cai Hui, Shu Xiao-Ou, Gao Yu-Tang, Xiang Yong-Bing, Van Den Berg David, Pike Malcom C, Wu Anna H, Pearce Celeste Leigh, Matsuo Keitaro

Abstract excerpt

The aldehyde dehydrogenase 2 (ALDH2) polymorphism rs671 (Glu504Lys) causes ALDH2 inactivation and adverse acetaldehyde exposure among Asians, but little is known of the association between alcohol consumption and rs671 and ovarian cancer (OvCa) in Asians. We conducted a pooled analysis of Asian ancestry participants in the Ovarian Cancer Association Consortium. We included seven case-control studies and one...

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Share to Adenocarcinoma, Mucinous
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Source

Open in PubMed Open full text

Identifiers

PMID: 29247577
DOI: 10.1111/cas.13470
PMCID: PMC5797830

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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