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Article

Teicoplanin resistance in Staphylococcus haemolyticus is associated with mutations in histidine kinases VraS and WalK.

Diagnostic microbiology and infectious disease - 1 Mar 2018

Vimberg Vladimir, Cavanagh Jorunn Pauline, Benada Oldřich, Kofroňová Olga, Hjerde Erik, Zieglerová Leona, Balíková Novotná Gabriela

Abstract excerpt

We investigated the genetic basis of glycopeptide resistance in laboratory-derived strains of S. haemolyticus with emphasis on differences between vancomycin and teicoplanin. The genomes of two stable teicoplanin-resistant laboratory mutants selected on vancomycin or teicoplanin were sequenced and compared to parental S. haemolyticus strain W2/124. Only the two non-synonymous mutations, VraS Q289K and WalK V550L...

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Identifiers

PMID: 29246777
DOI: 10.1016/j.diagmicrobio.2017.11.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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