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Article

Identification by genomic and genetic analysis of two new genes playing a key role in intermediate glycopeptide resistance in Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Mar 2009

Renzoni Adriana, Kelley William L, Barras Christine, Monod Antoinette, Huggler Elzbieta, François Patrice, Schrenzel Jacques, Studer René, Vaudaux Pierre, Lew Daniel P

Abstract excerpt

Endogenous, low-level glycopeptide resistance in Staphylococcus aureus results from multifactorial genetic changes. Comparative genomic hybridization analysis revealed the specific deletion of a 1.8-kb segment encompassing two adjacent open reading frames (ORFs) of unknown function in a teicoplanin-susceptible revertant (strain 14-4rev) compared to the sequence of its isogenic, teicoplanin-resistant parental...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19104009
DOI: 10.1128/AAC.01287-08
PMCID: PMC2650575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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