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Article

The GDNF Family: A Role in Cancer?

Neoplasia (New York, N.Y.) - 1 Jan 2018

Fielder Graeme C, Yang Teresa Wen-Shan, Razdan Mahalakshmi, Li Yan, Lu Jun, Perry Jo K, Lobie Peter E, Liu Dong-Xu

Abstract excerpt

The glial cell line-derived neurotrophic factor (GDNF) family of ligands (GFLs) comprising of GDNF, neurturin, artemin, and persephin plays an important role in the development and maintenance of the central and peripheral nervous system, renal morphogenesis, and spermatogenesis. Here we review our current understanding of GFL biology, and supported by recent progress in the area, we examine their emerging role...

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Source

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Identifiers

PMID: 29245123
DOI: 10.1016/j.neo.2017.10.010
PMCID: PMC5730419

Genes

GDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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