Article

Clinical phenotypes of uveal melanoma in patients with germline pathogenic/likely pathogenic <i>BAP1</i> variants

2026-07-01

Abstract excerpt

Germline pathogenic or likely pathogenic variants (GPVs) in BRCA-1 Associated Protein 1 ( BAP1 ) are associated with a spectrum of tumors, including uveal melanoma (UM). Currently, UM patients with BAP1 GPVs are treated as high-risk class 2 tumors based on mostly empiric data. In the current study, we examined the clinical phenotype of a cohort of 29 UM patients with BAP1 GPVs. We also carried out a systematic...

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Literature Corpus work: 89f21b1f-dd1b-5ace-ac71-fdc43e451fcf
DOI: 10.64898/2026.06.29.26356877

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