Article
FcɛR1α gene polymorphism shows association with high IgE and anti-FcɛR1α in Chronic Rhinosinusitis with Nasal Polyposis.
Journal of cellular biochemistry - 1 May 2018
Dar Sajad A, Rai Gargi, Ansari Mohammad A, Akhter Naseem, Gupta Neelima, Sharma Sonal, Haque Shafiul, Ramachandran Vishnampettai G, Wahid Mohd, Rudramurthy Shivprakash M, Chakrabarti Arunaloke, Das Shukla
Abstract excerpt
Despite large number of investigations, the etiology of chronic rhinosinusitis (CRS) remains unclear. Several factors are likely involved in its onset. The genetic susceptibility of IgE-responsiveness likely caused by polymorphism(s) in high affinity receptor for IgE (FcɛR1α) gene can help in understanding the pathophysiology of CRS with nasal polyposis (CRSwNP). A population-based case-control association...
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