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Article

IgE FcɛR1β polymorphism and risk of developing chronic spontaneous urticaria: A study in an ethnic Kashmiri population.

Allergologia et immunopathologia - 1 Jan 2000

Rasool R, Shera I A, Nissar S, Yousuf Q, Shah Z A

Abstract excerpt

BACKGROUND: The pathogenesis of chronic spontaneous urticaria involves interplay between the genetic and environmental factors, most of which is still poorly understood. It is well-recognized that 30-40% of chronic spontaneous urticaria is autoimmune in nature. Chronic autoimmune urticaria is caused by anti-FcɛR1β and less frequently, by anti-IgE auto antibodies that lead to mast cell and basophil activation,...

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PMID: 24953255
DOI: 10.1016/j.aller.2014.04.001

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