Article
Increased local IgE production induced by common aeroallergens and phenotypic alteration of mast cells in Chinese eosinophilic, but not non-eosinophilic, chronic rhinosinusitis with nasal polyps.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jan 2014
Cao P-P, Zhang Y-N, Liao B, Ma J, Wang B-F, Wang H, Zeng M, Liu W-H, Schleimer R P, Liu Z
Abstract excerpt
BACKGROUND: Eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps (CRSwNP) display distinct patterns of inflammation. However, the pathogenic mechanisms underlying the heterogeneity of CRSwNP need further investigation. OBJECTIVE: To investigate local immunoglobulin E (IgE) production and phenotype of mast cells in eosinophilic and non-eosinophilic CRSwNP in Chinese. METHODS: Total and...
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