Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signaling

31 Oct 2017

Abstract excerpt

// Heikki Kuusanmäki 1, 2 , Olli Dufva 2 , Elina Parri 1 , Arjan J. van Adrichem 1 , Hanna Rajala 2 , Muntasir M. Majumder 1 , Bhagwan Yadav 1 , Alun Parsons 1 , Wing C. Chan 3 , Krister Wennerberg 1 , Satu Mustjoki 2, 4, * and Caroline A. Heckman 1, * 1 Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland 2 Hematology Research Unit, Helsinki...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Lymphoma Diagnosis and Treatment
Share to T-cell and Retrovirus Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29228628
DOI: 10.18632/oncotarget.22178

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signalingPMID 29228628Read ↗

STAT3 Inhibitors: Finding a Home in Lymphoma and LeukemiaSemantic proximity Read ↗

Strategies and Approaches of Targeting STAT3 for Cancer TreatmentSemantic proximity Read ↗

JAK/STAT blockade reverses the malignant phenotype of Hodgkin and Reed-Sternberg cells.Semantic proximity Read ↗

Janus Kinase-Signal Transducer and Activator of Transcription Inhibitors for the Treatment and Management of CancerSemantic proximity Read ↗

Uncovering the pathogenesis of large granular lymphocytic leukemia-novel STAT3 and STAT5b mutations.Semantic proximity Read ↗

JAK kinase targeting in hematologic malignancies: a sinuous pathway from identification of genetic alterations towards clinical indications.Semantic proximity Read ↗

Small molecule STAT3/5 inhibitors exhibit therapeutic potential in acute myeloid leukemia and extra-nodal natural killer/T cell lymphomaSemantic proximity Read ↗

Small molecule STAT3/5 inhibitors exhibit therapeutic potential in acute myeloid leukemia and extra-nodal natural killer/T cell lymphomaSemantic proximity Read ↗

Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literatureSemantic proximity Read ↗

Janus Kinases in LeukemiaSemantic proximity Read ↗

Genomic Profiling of T-Cell Neoplasms Reveals Frequent JAK1 and JAK3 Mutations With Clonal Evasion From Targeted TherapiesSemantic proximity Read ↗

Molecular pathways: Jak/STAT pathway: mutations, inhibitors, and resistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.