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Article

An NF-κB signature predicts low-grade glioma prognosis: a precision medicine approach based on patient-derived stem cells

5 Dec 2017

Abstract excerpt

Background: While recent genome-wide association studies have suggested novel low-grade glioma (LGG) stratification models based on a molecular classification, we explored the potential clinical utility of patient-derived cells. Specifically, we assayed glioma-associated stem cells (GASC) that are patient-derived and representative of the glioma microenvironment. Methods: By next-generation sequencing, we...

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PMID: 29228370
DOI: 10.1093/neuonc/nox234

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