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Article

Tumor necrosis factor-α gene 308G/A polymorphism is not associated with esophageal squamous cell carcinoma risk in Kazakh patients.

International journal of clinical and experimental pathology - 1 Jan 2015

Cui Xiao-Bin, Wang Dan-Dan, Zhang Hai-Yang, Li Ting-Ting, Jin Ting-Ting, Peng Hao, Zhang Shu-Mao, Wang Bin, Yu Jie, Liu Chun-Xia, Yang Lan, Jin Jing, Li Su, Jiang Jin-Fang, Liang Wei-Hua, Hu Jian-Ming, Li Shu-Gang, Wu Chuan-Yue, Chen Yun-Zhao, Li Feng

Abstract excerpt

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a malignant tumor with a strong tendency toward familial aggregation and a higher incidence as well as mortality in Kazakh population. Tumor necrosis factor-alpha (TNF-α) is an important inflammatory cytokine that plays a role in controlling the progression of lung cancer, hepatocellular cancer, breast cancer and gastric cancer. But the association between...

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PMID: 26464679
PMCID: PMC4583911

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