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Article

Polygenic risk for alcohol consumption and its association with alcohol-related phenotypes: Do stress and life satisfaction moderate these relationships?

Drug and alcohol dependence - 1 Feb 2018

Mies Gabry W, Verweij Karin J H, Treur Jorien L, Ligthart Lannie, Fedko Iryna O, Hottenga Jouke Jan, Willemsen Gonneke, Bartels Meike, Boomsma Dorret I, Vink Jacqueline M

Abstract excerpt

BACKGROUND: Genetic and environmental factors contribute about equally to alcohol-related phenotypes in adulthood. In the present study, we examined whether more stress at home or low satisfaction with life might be associated with heavier drinking or more alcohol-related problems in individuals with a high genetic susceptibility to alcohol use. METHODS: Information on polygenic scores and drinking behavior was...

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Identifiers

PMID: 29220643
DOI: 10.1016/j.drugalcdep.2017.10.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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