Article
Characterization of PD-L1 expression in Chinese non-small cell lung cancer patients with PTEN expression as a means for tissue quality screening.
Cancer immunology, immunotherapy : CII - 1 Mar 2018
Zhang Xu-Chao, Cao Xu, Sun Chun, Xie Zhi, Guo Jian-Jun, Yang Jin-Ji, Yang Xue-Ning, Dai Hang-Jun, Li Su-Chun, Xu Xin-Ran, Zuo Yun-Xia, Chen Meng, Koeppen Hartmut, He Jing, Kiermaier Astrid, Shames David, Cheng Gang, Wu Yi-Long
Abstract excerpt
The goal of this study is to evaluate PD-L1 prevalence and its association with major clinical characteristics in Chinese non-small cell lung cancer (NSCLC) patients to inform the clinical development of anti-PD1/PD-L1 agents in this population. We used phosphatase and tensin homolog (PTEN) expression through IHC as a surrogate tissue quality marker to screen surgical NSCLC samples in tissue microarray (TMA; 172...
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