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Article

Temporal Effect on PD-L1 Detection and Novel Insights Into Its Clinical Implications in Non-Small Cell Lung Cancer.

Cancer medicine - 1 Oct 2024

Pathak Gopal P, Shah Rashmi, Castonguay Mathieu, Cheng Angela, Fris John, Murphy Rowan, Darling Gail, Ednie Alexander, French Daniel, Henteleff Harry, Mujoomdar Aneil, Plourde Madelaine, Wallace Alison, Xu Zhaolin

Abstract excerpt

OBJECTIVES: Several studies rely on archived tissue blocks to assess the PD-L1 scores; however, a detailed analysis of potential variations of scores between fresh and archived tissue blocks still lacks. In addition, the prognostic implications of PD-L1 in lung cancers have not yet been completely understood. Here, we aimed to investigate the temporal variation in PD-L1 scores from clinical samples and the...

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Identifiers

PMID: 39382248
DOI: 10.1002/cam4.70262
PMCID: PMC11462595

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