Article
PD-L1 Expression and Comprehensive Molecular Profiling Predict Survival in Nonsmall Cell Lung Cancer: A Real-World Study of a Large Chinese Cohort.
Clinical lung cancer - 1 Jan 2022
Jin Yan, Xue Qianqian, Shen Xuxia, Zheng Qiang, Chen Haiquan, Zhou Xiaoyan, Li Yuan
Abstract excerpt
BACKGROUND: Programmed death ligand 1 (PD-L1) expression is the current standard biomarker used to predict non-smallcell lung cancer (NSCLC) response to immunotherapy. Gene expression signatures also seem to be related to the response to immunotherapy. Understanding the clinical and prognostic impact of molecular phenotype and tumor features on PD-L1 expression in NSCLC patients may improve the prediction of...
Topics
- B7-H1 Antigen
- Carcinoma, Non-Small-Cell Lung
- China
- Female
- Genes, erbB-1
- Genetic Profile
- Humans
- Immunotherapy
- Lung Neoplasms
- Male
- Mutation