Article
Association Study of MECP2 Gene Single Nucleotide Polymorphisms in Juvenile-Onset Systemic Lupus Erythematosus Patients from Iran.
Fetal and pediatric pathology - 1 Dec 2017
Mahmoudi Mahdi, Aslani Saeed, Hamzeh Elham, Ziaee Vahid, Poursani Shiva, Nicknam Mohammad Hossein, Rezaei Nima
Abstract excerpt
INTRODUCTION: Juvenile-onset systemic lupus erythematosus is a multigenic autoimmune disorder. Polymorphisms of MECP2 gene have been reported to increase the risk of adult-onset SLE. In this study, we aimed to analyze if MECP2 gene polymorphisms could impress the proneness to JSLE in Iranian population. MATERIAL AND METHODS: Polymorphisms of MECP2 gene were genotyped in 50 Iranian JSLE patients and 426 matched...
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