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Article

An ARV1 homologue from a filarial nematode is functional in yeast.

Journal of helminthology - 1 Jan 2019

Herath H M L P B, Gunawardene Y I N S, Pathiranage M, Wickramasinghe P D S U, Wickramatunge P G T S, Dassanayake R S

Abstract excerpt

The transmembrane protein, ARV1, plays a key role in intracellular sterol homeostasis by controlling sterol distribution and cellular uptake. To date, only the ARV1s from yeast and humans have been characterized to some extent. In this study, the ARV1 of an animal filarial parasite, Setaria digitata (SdARV1), was characterized; its cDNA was 761 bp and encoded a protein of 217 amino acids, with a predicted...

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Source

Identifiers

PMID: 29183411
DOI: 10.1017/S0022149X17001109

Genes

ARV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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