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Role of microRNA-33a in regulating the expression of PD-1 in lung adenocarcinoma

17 Nov 2017

Abstract excerpt

MiRNAs are vital in functioning as either oncogenes or tumor suppressors in the cell cycle. Target transcripts for immune checkpoint molecules such as PD-1/PD-L1 and (programmed cell death-1/its ligand and cytotoxic T-lymphocyte antigen 4) have proven to be beneficial against several solid tumors, including lung adenocarcinoma. Simultaneous quantification of the expression level of miR-33a and PD-1, PD-L1 and...

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PMID: 29176936
DOI: 10.1186/s12935-017-0474-y

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