Back to search

Article

PD-L1 and TP-53 mRNA and microRNAs Expression in Liquid Biopsy of NSCLC Patients.

2021-02-05

Abstract excerpt

<h4>Introduction: </h4> The expression of PD-L1 (programed cell death ligand 1) protein on neoplastic cells is a factor qualifying cancer patients for immunotherapy. However, the status of PD-L1 mRNA expression in plasma or serum has not been well studied in cancer patients. TP-53 (Tumor Protein p53) as tumor suppressor affects the expression of many genes, including microRNAs that regulate PD-L1 expression. The p...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
fa7c9fab-dba0-5e90-8d84-206f5f7506b5
DOI
10.21203/rs.3.rs-153178/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
PD-L1 and TP-53 mRNA and microRNAs Expression in Liquid Biopsy of NSCLC Patients.DOI 10.21203/rs.3.rs-153178/v1
Diagnostic Utility of PD-L1 and TP-53 mRNA As Well As microRNAs Expression in Liquid Biopsy of NSCLC Patients – Pilot StudySemantic proximity
Exploring the Impact of TP53 Mutation and Wild-Type Status on the Efficacy of Immunotherapy in Non-Small Cell Lung CancerSemantic proximity
PD-L1 gene polymorphism and high level of plasma soluble PD-L1 protein may be associated with non-small cell lung cancer.Semantic proximity
Role of microRNA-33a in regulating the expression of PD-1 in lung adenocarcinomaSemantic proximity
[The detection of Rb2/p130 and p53 gene mutations by denaturing high-performance liquid chromatography analysis of sputum of lung cancer patients and its clinical implications].Semantic proximity
Monitoring PD-L1 positive circulating tumor cells in non-small cell lung cancer patients treated with the PD-1 inhibitor Nivolumab.Semantic proximity
P53 and NLR could recognize distinct subtypes of lung adenocarcinoma with high expression of PD-L1 (TPS≥50%) defined by 22C3Semantic proximity
The Implication of Liquid Biopsy in the Non-small Cell Lung Cancer: Potential and Expectation.Semantic proximity
Select a neighboring publication to make it the new centre.