Article
Risk of Cardiac Events Associated With Antidepressant Therapy in Patients With Long QT Syndrome.
The American journal of cardiology - 15 Jan 2018
Wang Meng, Szepietowska Barbara, Polonsky Bronislava, McNitt Scott, Moss Arthur J, Zareba Wojciech, Auerbach David S
Abstract excerpt
Patients with long QT syndrome (LQTS) are at a high risk of cardiac events. Many patients with LQTS are treated with antidepressant drugs (ADs). We investigated the LQTS genotype-specific risk of recurrent cardiac arrhythmic events (CAEs) associated with AD therapy. The study included 59 LQT1 and 72 LQT2 patients from the Rochester-based LQTS Registry with corrected QT (QTc) prolongation and a history of AD...
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