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Article

Low incidence of precore W28* mutant variants in treated hepatitis B virus and human immunodeficiency virus co-infected patients.

Antiviral research - 1 Jan 2018

Boyd Anders, Lacombe Karine, Lavocat Fabien, Miailhes Patrick, Lascoux-Combe Caroline, Girard Pierre-Maire, Zoulim Fabien

Abstract excerpt

The precore (pc) W28* mutation arises from immune-selective pressures during the hepatitis B "e" antigen (HBeAg)-positive phase of chronic hepatitis B virus (HBV) infection and has been linked to severe liver-related morbidity. Here, we examined the determinants of harboring this mutation and its rate of emergence in treated patients co-infected with human immunodeficiency virus (HIV) and HBV. In a three-year...

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Identifiers

PMID: 29169914
DOI: 10.1016/j.antiviral.2017.11.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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