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New WS9326A Derivatives and One New Annimycin Derivative with Antimalarial Activity are Produced by Streptomyces asterosporus DSM 41452 and Its Mutant.

Chembiochem : a European journal of chemical biology - 2 Feb 2018

Zhang Songya, Zhu Jing, Zechel David L, Jessen-Trefzer Claudia, Eastman Richard T, Paululat Thomas, Bechthold Andreas

Abstract excerpt

In this study, we report that Streptomyces asterosporus DSM 41452 is a producer of new molecules related to the nonribosomal cyclodepsipeptide WS9326A and the polyketide annimycin. S. asterosporus DSM 41452 is shown to produce six cyclodepsipeptides and peptides, WS9326A to G. Notably, the compounds WS9326F and WS9326G have not been described before. The genome of S. asterosporus DSM 41452 was sequenced, and a...

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PMID: 29148157
DOI: 10.1002/cbic.201700428
PMCID: PMC6324189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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