Article
Geissoschizine synthase controls flux in the formation of monoterpenoid indole alkaloids in a Catharanthus roseus mutant.
Planta - 1 Mar 2018
Qu Yang, Thamm Antje M K, Czerwinski Matthew, Masada Sayaka, Kim Kyung Hee, Jones Graham, Liang Ping, De Luca Vincenzo
Abstract excerpt
MAIN CONCLUSION: A Catharanthus roseus mutant accumulates high levels of ajmalicine at the expense of catharanthine and vindoline. The altered chemistry depends on increased expression and biochemical activities of strictosidine β-glucosidase and ajmalicine synthase activities and reduced expression and biochemical activity of geissoschizine synthase. The Madagascar periwinkle [Catharanthus roseus (L.) G. Don] is...
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