Article
A tabersonine 3-reductase Catharanthus roseus mutant accumulates vindoline pathway intermediates.
Planta - 1 Jan 2018
Edge Alison, Qu Yang, Easson Michael L A E, Thamm Antje M K, Kim Kyung Hee, De Luca Vincenzo
Abstract excerpt
MAIN CONCLUSION: Monoterpenoid indole alkaloids (MIAs) have remarkable biological properties that have led to their medical uses for a variety of human diseases. Mutagenesis has been used to generate plants with new alkaloid profiles and a useful screen for rapid comparison of MIA profiles is described. The MIA mutants identified are useful for investigating MIA biosynthesis and for targeted production of these...
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