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Article

Association of a variant in the gene encoding for ERV1/ChemR23 with reduced inflammation in visceral adipose tissue from morbidly obese individuals.

Scientific reports - 16 Nov 2017

López-Vicario Cristina, Rius Bibiana, Alcaraz-Quiles José, González-Périz Ana, Martínez-Puchol Ana Isabel, Casulleras Mireia, Duran-Güell Marta, Ibarzabal Ainitze, Corcelles Ricard, Laguna-Fernández Andrés, Back Magnus, Titos Esther, Clària Joan

Abstract excerpt

Obesity comorbidities are closely associated with chronic low-grade adipose tissue inflammation. A number of SNPs associated with inflammation has been identified, underscoring the impact of genetic determinants on this process. Here, we screened SNPs in genes with pro-inflammatory (IL-1β, IL-6, STAT3 and JAK2), anti-inflammatory (IL-10 and SOCS3) and pro-resolving (ERV1/ChemR23) properties in 101 obese and 99...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29146976
DOI: 10.1038/s41598-017-15951-z
PMCID: PMC5691181

Genes

JAK2
SOCS3
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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