Article

Evidence from studies in rodents and in isolated adipocytes that agonists of the chemerin receptor CMKLR1 may be beneficial in the treatment of type 2 diabetes

2014-11-28

Abstract excerpt

It is unclear whether the adipokine chemerin has pro- or anti-inflammatory properties, plays any role in the aetiology of obesity or type 2 diabetes, or whether agonists or antagonists of the chemerin receptor CMKLR1 have potential in the treatment of these diseases. To address these questions, we investigatedthe metabolic phenotypes of both male and female, CMKLR1 knockout and heterozygote mice; the effects of mu...

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Literature Corpus work: 9baaa340-888e-516b-9f7a-ef81b054b1f1
DOI: 10.7287/peerj.preprints.643v1

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