Article
Characterization of clinically isolated thymidine-dependent small-colony variants of Escherichia coli producing extended-spectrum β-lactamase.
Journal of medical microbiology - 1 Jan 2018
Negishi Tatsuya, Matsumoto Takehisa, Horiuchi Kazuki, Kasuga Eriko, Natori Tatsuya, Matsuoka Mina, Ogiwara Naoko, Sugano Mitsutoshi, Uehara Takeshi, Nagano Noriyuki, Honda Takayuki
Abstract excerpt
PURPOSE: Thymidine-dependent small-colony variants (TD-SCVs) are difficult to detect or test for antimicrobial susceptibility. We investigated the characteristics of clonal TD-SCVs of Escherichia coli, both with and without blaCTX-M-3, isolated from a patient. METHODOLOGY: Mutation in the thyA gene was analysed by sequencing, and morphological abnormalities in the colonies and cells of the isolates were examined....
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