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Article

Influence of phosphatidylserine and phosphatidylethanolamine on farnesol tolerance in Candida albicans.

Yeast (Chichester, England) - 1 Apr 2018

Hasim Sahar, Vaughn Elyse N, Donohoe Dallas, Gordon Donna M, Pfiffner Susan, Reynolds Todd B

Abstract excerpt

Candida albicans is among the most common human fungal pathogens. The ability to undergo the morphological transition from yeast to hyphal growth is critical for its pathogenesis. Farnesol, a precursor in the isoprenoid/sterol pathway, is a quorum-sensing molecule produced by C. albicans that inhibits hyphal growth in this polymorphic fungus. Interestingly, C. albicans can tolerate farnesol concentrations that...

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Identifiers

PMID: 29143357
DOI: 10.1002/yea.3297
PMCID: PMC5893404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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