Article
The industrial anaerobe Clostridium acetobutylicum uses polyketides to regulate cellular differentiation.
Nature communications - 15 Nov 2017
Herman Nicolaus A, Kim Seong Jong, Li Jeffrey S, Cai Wenlong, Koshino Hiroyuki, Zhang Wenjun
Abstract excerpt
Polyketides are an important class of bioactive small molecules valued not only for their diverse therapeutic applications, but also for their role in controlling interesting biological phenotypes in their producing organisms. While numerous polyketides are known to be derived from aerobic organisms, only a single family of polyketides has been identified from anaerobic organisms. Here we uncover a family of...
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