Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Discovery of Clostrubin, an Exceptional Polyphenolic Polyketide Antibiotic from a Strictly Anaerobic Bacterium

14 May 2014

Abstract excerpt

Genome mining of the strictly anaerobic bacterium Clostridium beijerinckii, an industrial producer of solvents, revealed the presence of several cryptic gene clusters for secondary metabolite biosynthesis. To unearth its metabolic potential, a C. beijerinckii strain was cultured under various conditions, which led to the discovery of a deep purple pigment. This novel metabolite, named clostrubin (1), was isolated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fungal Biology and Applications
Share to Genomics and Phylogenetic Studies
Share to Microbial Natural Products and Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24827417
DOI: 10.1002/anie.201402632

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Discovery of Clostrubin, an Exceptional Polyphenolic Polyketide Antibiotic from a Strictly Anaerobic BacteriumPMID 24827417Read ↗

The industrial anaerobe Clostridium acetobutylicum uses polyketides to regulate cellular differentiation.Semantic proximity Read ↗

Triumphs and Challenges of Natural Product Discovery in the Postgenomic EraSemantic proximity Read ↗

Investigation of the Molecular Landscape of Bacterial Aromatic Polyketides by Global Analysis of Type II Polyketide SynthasesSemantic proximity Read ↗

Genomic Analysis of Endophytic Bacillus-Related Strains Isolated from the Medicinal Plant Origanum vulgare L. Revealed the Presence of Metabolic Pathways Involved in the Biosynthesis of Bioactive CompoundsSemantic proximity Read ↗

Pattern-based genome mining guides discovery of the antibiotic indanopyrrole A from a marine streptomyceteSemantic proximity Read ↗

Complete Genome of Micromonospora sp. Strain B006 Reveals Biosynthetic Potential of a Lake Michigan ActinomyceteSemantic proximity Read ↗

Genomics-inspired discovery of natural products.Semantic proximity Read ↗

High-throughput screening identifies a novel natural product-inspired scaffold capable of inhibiting Clostridioides difficile in vitroSemantic proximity Read ↗

Cryptic Polyketide Synthase Genes in Non-Pathogenic Clostridium SPPSemantic proximity Read ↗

A Hybrid Type I and II Polyketide Synthases Yields Distinct Aromatic PolyketidesSemantic proximity Read ↗

Discovery and Biosynthesis of the Antibiotic Bicyclomycin in Distantly Related Bacterial ClassesSemantic proximity Read ↗

Discovery and biosynthesis of the antibiotic bicyclomycin in distant bacterial classesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.