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Article

Molecular Landscape of Non-Muscle Invasive Bladder Cancer.

Cancer cell - 13 Nov 2017

Meeks Joshua J, Lerner Seth P

Abstract excerpt

In this issue of Cancer Cell, Hurst et al. report an integrated analysis of non-invasive (stage Ta) bladder cancer. Two genomic subtypes are distinguished by chromosome 9q loss, resulting in increased AKT/PI3K/mTOR signaling. Tumors from female patients have a higher frequency of KDM6A mutations.

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Identifiers

PMID: 29136502
DOI: 10.1016/j.ccell.2017.08.015

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