Article
Testing gene-treatment interactions in pharmacogenetic studies.
Journal of biopharmaceutical statistics - 1 Mar 2010
He Min, Allen Andrew
Abstract excerpt
Drug-related side effects are one of the leading causes of death and illness in the developed world. Finding genes that modify drug response has the potential to significantly improve drug delivery, by identifying both individuals that can benefit from therapy and those at increased risk of harm. We present a simple approach to testing gene-by-treatment interactions in case-control pharmacogenetic studies. The...
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