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Article

Osteoclast-like giant cells in invasive breast cancer predominantly possess M2-macrophage phenotype.

Pathology, research and practice - 1 Feb 2018

Ohashi Ryuji, Yanagihara Keiko, Namimatsu Shigeki, Sakatani Takashi, Takei Hiroyuki, Naito Zenya, Shimizu Akira

Abstract excerpt

Breast carcinoma with osteoclast-like giant cells (OGCs) is a rare tumor; however, their clinicopathological aspects remain unclear. We described the clinicopathological characteristics of 8 patients with breast carcinoma with OGCs. Immuno-phenotypes of the OGCs were comparatively examined with that of foreign body giant cells (FBGCs) in 4 cases of granulomatous reaction (GR) without cancerous elements. In most...

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Identifiers

PMID: 29129494
DOI: 10.1016/j.prp.2017.11.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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