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Article

Cytologic Features of Malignant Melanoma with Osteoclast-Like Giant Cells.

Acta cytologica - 1 Jan 2018

Jiménez-Heffernan José A, Adrados Magdalena, Muñoz-Hernández Patricia, Fernández-Rico Paloma, Ballesteros-García Ana I, Fraga Javier

Abstract excerpt

BACKGROUND: Malignant melanoma showing numerous osteoclast-like giant cells (OGCs) is an uncommon morphologic phenomenon, rarely mentioned in the cytologic literature. The few reported cases seem to have an aggressive clinical behavior. Although most findings support monocyte/macrophage differentiation, the exact nature of OGCs is not clear. CASE: A 57-year-old woman presented with an inguinal lymphadenopathy....

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Source

Identifiers

PMID: 29332062
DOI: 10.1159/000486027

Genes

BRAF
SOX10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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